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JWH-018 is more robust than THC or tetrahydrocannabinol, The crucial element Lively component in cannabis. A small dose is adequate to induce an intoxicating influence. JWH-018 binds the CB1 receptor four occasions a lot more tightly and also the CB2 receptor 10 moments much more tightly than THC.When smoked, the onset of effect is amazingly speedy